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Intrauterine growth restriction and spontaneous abortion are already documented with modafinil and armodafinilNo unique dose adjustment suggested when tofacitinib coadministered with potent CYP2C19 inhibitors; lessen tofacitinib dose if coadministered with each reasonable CYP3A4 and potent CYP2C19 inhibitors .Modafinil can be accessible to astronau